Journal: PLoS ONE

Article Title: Cyclooxgenase-2 Inhibiting Perfluoropoly (Ethylene Glycol) Ether Theranostic Nanoemulsions— In Vitro Study

doi: 10.1371/journal.pone.0055802

Figure Lengend Snippet: Composition of nanoemulsions.

Article Snippet: CellVue® NIR815 (786 nm/814 nm) and CellVue® Burgundy (683 nm/707 nm) Fluorescent Cell Linker Kit was purchased from Molecular Targeting Technologies, Inc. (MTTI), West Chester, PA, USA.

Techniques:

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Structural formula of PSVue®794, a zinc(II) dipicolylamine probe.

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques:

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Dynamic optical images of one mouse bearing bacterial infection were acquired for 10 s at 5 min and at 1, 2, and 3 h post-tail vein injection of PSVue®794. Ratios of intensity in abscess to contralateral thigh (A/CL) are given. Declining uptake in liver and kidneys is visible as a function of time after injection.

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Infection, Injection

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Posterior optical images of mice with turpentine-induced inflammation. Ten-second images were acquired at 2 and 4 h post-tail vein administration of 2.7 pmol of PSVue®794. During intravenous injection, a small quantity of PSVue®794 was infiltrated, which is visible. The presence of the probe in the left leg was external contamination (x-ray images are not shown).

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Injection

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Posterior optical images of mice with bacterial infection in the right thigh. Ten-second images were obtained at 2 and 4 h post-intravenous administration of 2.7 pmol PSVue®794 (x-ray images are not shown). A small amount of the fluorophore infiltration of the probe in the tail during injection is visible.

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Infection, Injection

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Confocal microscopic images of a normal and b PSVue®794-incubated normal white blood cells. Apoptotic white blood cells (c) with intense PSVue®794 fluorescence specific for phosphatidylserine (d) (×63).

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Incubation, Fluorescence

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Confocal microscopic images of a normal gram-positive Staphylococcus lugdunensis. b In normal S. lugdunensis incubated with PSVue®794, fluorescence is detectable. c Confocal microscopic image of the microorganism. d Uptake of PSVue®794 in the apoptotic bacteria (×400).

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Incubation, Fluorescence, Bacteria

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Article Title: Targeting Apoptosis for Optical Imaging of Infection

doi: 10.1007/s11307-011-0490-6

Figure Lengend Snippet: Confocal microscopic images of a normal E. coli gram-negative and c apoptotic E. coli. b Normal E. coli after incubation with PSVue®794. No bacterial fluorescence is detectable. d Poor fluorophore uptake in the apoptotic E. coli (ATCC-29213) (×400).

Article Snippet: A 1 mM solution of PSVue ® 794, the structural formula of which is given in , was prepared according to the procedure provided by the supplier (Molecular Targeting Technologies, Inc., West Chester, PA).

Techniques: Incubation, Fluorescence

Journal: Journal of Nuclear Medicine

Article Title: Advancing Targeted Radionuclide Therapy Through the National Cancer Institute’s Small Business Innovation Research Pathway

doi: 10.2967/jnumed.118.214684

Figure Lengend Snippet: NCI SBIR–Funded TRT Contracts from 2016 to 2017

Article Snippet: 2017 , Molecular Targeting Technologies, Inc. , Phase I , Glioblastoma , Radioiodine , SapC-DOPS nanovesicles , Create novel cancer-selective, targeted, radiolabeled SapC-DOPS for treatment of glioblastoma.

Techniques: Radioactivity, Drug discovery, Recombinant, Biomarker Discovery, In Vivo, Fluorescence, Binding Assay, Labeling, In Vitro, Produced, Software

Journal: Neuron

Article Title: Rewiring of human neurodevelopmental gene regulatory programs by Human Accelerated Regions (HARs)

doi: 10.1016/j.neuron.2021.08.005

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: CaptureMPRA library design, cloning, and transfection Molecular Inversion Probes (MIPs) targeting flanking regions of all HAR sequences were designed using the MIPgen program ( Boyle et al., 2014 ) and manufactured as a pool by CustomArray (Bothell, WA).

Techniques: Virus, Recombinant, Electron Microscopy, Modification, Lysis, Sonication, Plasmid Preparation, Software

Journal: Neuron

Article Title: Rewiring of human neurodevelopmental gene regulatory programs by Human Accelerated Regions (HARs)

doi: 10.1016/j.neuron.2021.08.005

Figure Lengend Snippet: KEY RESOURCES TABLE

Article Snippet: CaptureMPRA library design, cloning, and transfection Molecular Inversion Probes (MIPs) targeting flanking regions of all HAR sequences were designed using the MIPgen program ( Boyle et al., 2014 ) and manufactured as a pool by CustomArray (Bothell, WA).

Techniques: Virus, Recombinant, Electron Microscopy, Modification, Lysis, Sonication, Plasmid Preparation, Software